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Gustatory Sweating and DryDerm G wipes
There are several different forms or types of Gustatory Hyperhidrosis. These are all somewhat similar and involve excessive sweating in the facial, scalp and neck regions. Unlike focal hyperhidrosis, gustatory sweating is episodic and is associated with eating, smelling and/or even thinking of food and/or drink.
Although several treatments exists, we will review the clinical proof behind the use of the key ingredient in DryDerm G, that is glycopyrrolate (GLI-KO-PI-RO-LATE). There are very few studies that examine the use of glycopyrrolate in the treatment of gustatory sweating. Having said this, these studies have determined that topically applied glycopyrrolate is very effective and very safe. Click here to access our review page on Gustatory Hyperhidrosis.
Primary Gustatory Sweating
A clinical study* looked at the use of topically applied glycopyrrolate in individuals with primary gustatory sweating (i.e. gustatory sweating with unknown cause or not associated with any other condition) . Investigators in this study measured actual sweat production from individuals with a placebo cream applied to one half of the face and glycopyrrolate to the other. Sweat production on the glycopyrrolate side was about 1/3 compared to the placebo side.
Compensatory Gustatory Sweating
About 3/4 of individuals that undergo a sympathectomy will develop compensatory sweating. Of those, a certain proportion (anywhere between 10 to 36%) will exhibit gustatory hyperhidrosis.
A study* involving individuals with compensatory gustatory hyperhidrosis applied glycopyrrolate for 2 to 3 weeks and were asked to evaluate their experience. Treatment effect was *Kim WO, et.al. Br J Dermatol, 2008 **Won-Oak K, et. al. Yonsei Med J, 2003
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Diabetic Gustatory Sweating
Glycopyrrolate also reduced the frequency of sweating episodes by a little over one half (51%). The frequency of severe episodes of sweating was practically totally eliminated (almost 100%).
* Shaw JE, et. al. Diabetalogia, 1997
DryDerm G Facial Wipes The Dry Pharmacist offers glycopyrrolate or DryDerm G wipes in two strengths, that is 1% and 2% formulations. We recommend starting with the 1% formulation and if your condition appears to be responding but you think it may require additional treatment then you can opt for the 2% strength.
DryDerm G is relatively expensive. The reason is that glycopyrrolate, the active ingredient in DryDerm G, is an expensive product to manufacture. We adhere to the use of pharmaceutical or the USP* grade of glycopyrrolate. Despite this, we have done our best to keep the price as low as possible in efforts to make the product affordable to most individuals with gustatory sweating or gustatory hyperhidrosis. * United States Pharmacopeia DryDerm G wipes.
For gustatory and compensatory sweating. |